C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61K 38/57 (2006.01) C07K 1/14 (2006.01) C07K 14/475 (2006.01) C07K 14/81 (2006.01) C12N 15/15 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2137377
The present invention relates to a purified retinal pigmented epithelium derived neurotrophic factor composition and a method for purifying such a retinal pigmented epithelium neurotrophic factor. The present invention also relates to a recombi-nant DNA molecule comprising a gene encoding a retinal pigmented epithelium derived neurotrophic factor having the DNA se-quence or the amino acid sequence in SEQ ID NO 1 and to an organism transformed with the recombinant DNA molecule. In addition, the present invention relates to a method of treating tumors, ocular diseases, nerve injuries, and conditions resulting from the activity of serine proteases, which comprises administering retinal epithelium derived neurotrophic factor.
Becerra Sofia Patricia
Chader Gerald J.
Johnson Lincoln V.
Steele Fintan R.
Tombran-Tink Joyce
Department Of Health And Human Services The Government Of The United States Of America As Represented By
Smart & Biggar
The University Of Southern California
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