A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2335007
Nucleic acid sequences and corresponding polypeptides that are expressed by lung tissue, the expression of which is induced by retinoic acid or inhibited by retinoic acid, are provided. These polypeptide sequences, and the human counterparts, can be used to promote cell differentiation and/or proliferation, especially of alveolar tissue. Also, these cDNAs can be used to identify other retinoic acid inducible sequences.
L'invention concerne des séquences d'acide nucléique et des polypeptides associés qui sont exprimés par du tissu pulmonaire et dont l'expression est induite ou inhibée par l'acide rétinoïque. Ces séquences de polypeptides et leurs équivalents humains peuvent servir à favoriser la différenciation et la prolifération cellulaires, notamment d'un tissu alvéolaire. En outre, ces ADN complémentaires peuvent servir à identifier d'autres séquences inductibles par acide rétinoïque.
Chan Wai-Yee
Georgetown University Medical Center
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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