Retinoid-associated receptor function regulating agent

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 263/30 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) C07D 263/32 (2006.01) C07D 277/30 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2332178

Retinoid-associated receptor regulators containing 1,3-azole derivatives represented by general formula (I) or salts thereof wherein R1 represents optionally substituted aromatic hydrocarbyl or heteroaryl; R2 represents hydrogen or optionally substituted hydrocarbyl; X represents O, s or -NR4-; A represents optionally substituted aromatic hydrocarbyl or heteroaryl; and R3 represents -OR5 or -NR6R7. These products are usable as, for example, preventives and remedies for diabetes, etc.

On décrit des régulateurs du récepteur associé aux rétinoïdes contenant des dérivés 1,3-azole représentés par la formule (I) ou des sels de ces derniers. Dans la formule, R?1¿ représente hydrocarbyle ou hétéroaryle aromatique facultativement substitué; R?2¿ représente hydrogène ou hydrocarbyle facultativement substitué; X représente O, s ou -NR?4¿-; A représente hydrocarbyle ou hétéroaryle aromatique facultativement substitué; et R?3¿ représente -OR?5¿ ou -NR?6¿R?7¿. Ces produits peuvent être utilisés, par exemple, en tant que produits préventifs ou de traitement pour le diabète et d'autres maladies.

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