Retinoid-like heterocycles

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 333/24 (2006.01) A61K 31/33 (2006.01) C07D 207/337 (2006.01) C07D 213/30 (2006.01) C07D 213/55 (2006.01) C07D 213/56 (2006.01) C07D 215/12 (2006.01) C07D 215/14 (2006.01) C07D 217/14 (2006.01) C07D 217/16 (2006.01) C07D 231/12 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01) C07D 237/08 (2006.01) C07D 239/26 (2006.01) C07D 241/12 (2006.01) C07D 263/32 (2006.01) C07D 277/30 (2006.01) C07D 307/54 (2006.01)

Patent

CA 2173047

This invention relates to compounds of formula I Image (I) in which T is -CONH- or -CH=CH-; Ra and Rb are independently C1-6 alkyl; Rc is C1-6 alkyl or hydrogen; and R is heteroaryl. These compounds are useful for preventing and/or treating various skin disorders, such as, but not limited to, acne, psoriasis and damage from irradiation. Further, they have antitumor activities.

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