A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/44 (2006.01) A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 9/08 (2006.01) A61K 9/107 (2006.01) A61K 9/12 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 9/70 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 31/425 (2006.01) A61K 31/455 (2006.01) A61K 45/06 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2284192
Methods for treating and/or preventing non-insulin dependent diabetes mellitus (NIDDM) in subjects having or at substantial risk of developing NIDDM, using specific retinoid compounds that are structurally related to 9-cis retinoid acid which induce the differentiation of preadipocytes into adipocytes, are provided. These compounds may be administered alone or in combination with other anti-diabetogenic agents such as thiazolidinediones.
La présente invention concerne des procédés permettant de traiter et/ou de prévenir le diabète sucré non-insulinodépendant chez des sujets souffrant de cette maladie ou présentant un risque important de la développer. Lesdits procédés font appel à des composés rétinoïdes spécifiques structurellement apparentés à l'acide rétinoïque 9-cis qui induit la différenciation des préadipocytes en adipocytes. Ces composés peuvent être administrés seuls ou en combinaison avec d'autres agents antidiabetogènes tels que les thiazolidinediones.
Fanjul Andrea
Lernhardt Waldemar
Pfahl Magnus
Galderma Research & Development S.n.c.
Robic
LandOfFree
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