Retinol stabilized cleansing compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 8/67 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2285812

The present invention provides compositions which include (A) a skin enhancing agent; (B) glycerin; (C) one or more emollients; and (D) a salt of cocoyl isethionate, a mono alkyl phosphate or a salt thereof, or a combination thereof, neutralized to a pH ranging from about 5 to about 8. In an alternate embodiment, the present invention provides compositions described above which further include (E) water; (F) a gum; (G) a gum neutralized to a pH ranging from about 5 to about 8; (H) a detergent additive selected from the group consisting of sodium lauryl sulfate, a sodium salt of fatty acid taurate, an acyl glutamate, an alpha-olefin sulfonate, a sarcosinate, or any combination of any of the foregoing; (I) a mixture of diosodium cocamido monoethanolamine sulfosuccinate and cocamido betaine; (J) an anti- microbial agent; (K) microcrystalline wax; (L) a foam booster; (M) an antioxidant; (N) a UV stabilizer; (O) a sun screen; (P) a colorant; (Q) a fragrance; (R) a preservative; (S) a chelating agent; (T) a physical exfolliant; or (U) any combination of any of the foregoing. These compositions are useful in preparing stable formulations containing pH dependent active agents including, but not limited to, retinol. Also provided are methods of delivering skin-enhancing agents, such as retinol, to an animal, preferably a mammal, and most preferably a human, by topically applying the compositions of the present invention to the skin of an animal in need of the skin enhancing agent.

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