Retro-inverso analogues of c-terminal penta and hexapeptides...

C - Chemistry – Metallurgy – 07 – K

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530/9, 530/5.04,

C07K 7/06 (2006.01) C07K 5/02 (2006.01) C07K 7/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1249698

"Retro-inverso analogues of C-terminal penta and hexapeptides of substance P" Abstract of the disclosure This invention relates to new retro-inverso peptides and peptide derivatives in the form of analogues of the C-terminal penta and hexapeptide fragments of Substance P, which are pharmacologically active, possess prolonged action with time and are useful as vasodilators, their general formula being: P - R5 - NH - Image - NH - CO - Image - CO - R2 - R1 - NH2

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