Retrograde delivery catheter and method for inducing...

A - Human Necessities – 61 – M

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A61M 29/00 (2006.01) A61B 17/28 (2006.01) A61M 25/00 (2006.01) A61B 17/00 (2006.01) A61B 17/32 (2006.01)

Patent

CA 2208350

A retrograde delivery catheter (10) includes at its distal end a balloon (11) configured to occlude the coronary sinus (21) of a patient's heart, and has a length and flexibility which allow the distal end to be positioned in the coronary sinus (21) with the proximal end extending trans-luminal to a peripheral vein such as an internal jugular vein (44) and out of the body through a puncture (24) therein. The delivery catheter (20) has a delivey lumen (128) extending between its proximal and distal ends which is configured to allow a cardioplegia fluid to be delivered at a flow rate of at least 200 ml/min with a pump pressure less than 300 mm Hg, thereby allowing cardioplegia arrest to be maintained using a blood cardioplegia fluid without causing excessive hemolysis. In a method of inducing cardioplegia arrest according to the invention, the patient is placed on cardiopulmonary bypass (18), the coronary arteries (50, 51) are isolated from remainder of the arterial system, and the delivery catheter (10) is positioned trans-luminal in the coronary sinus (21) from a peripheral vein.

Cathéter (10) d'administration par voie rétrograde ayant à son extrémité distale un ballonnet (11) configuré de façon à occlure le sinus coronaire (21) du coeur d'un patient, et dont la longueur et la souplesse permettent de positionner l'extrémité distale dans le sinus coronaire (21), l'extrémité proximale s'étendant de manière transluminale jusqu'à une veine périphérique telle que la veine jugulaire interne (44), et hors du corps par une ponction (24) pratiquée dans ce dernier. Le cathéter d'administration (20) présente une lumière d'administration (128) qui s'étend entre ses extrémités proximale et distale, lumière configurée de façon à permettre l'administration d'un liquide de cardioplégie à un débit d'au moins 200 ml/min avec une pression de refoulement de pompe inférieure à 300 mm Hg, ce qui permet le maintien de la cardioplégie à l'aide d'un liquide sanguin de cardioplégie sans provoquer une hémolyse excessive. Dans un procédé d'induction de la cardioplégie selon l'invention, le patient est placé en circulation extra-corporelle (18), les artères coronaires (50, 51) sont isolées du reste du système artériel et le cathéter d'administration (10) est disposé de façon transluminale dans le sinus coronaire (21) à partir d'une veine périphérique.

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