C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) C07K 14/15 (2006.01) C07K 14/47 (2006.01)
Patent
CA 2295935
The invention concerns a nucleic material, in isolated or purified state, and a nucleotide fragment comprising a nucleotide sequence selected from the group consisting in (i) the sequences SEQ ID NO: 112, SEQ ID NO:114, SEQ ID NO: 117, SEQ ID NO: 120, SEQ ID NO. 124, SEQ ID NO: 130, SEQ ID NO: 141 and SEQ ID NO: 142, (ii) the complementary sequences of sequences (i); and (iii) the sequences equivalent to sequences (ii) and (iii), in particular the sequence having for every series of 100 contiguous monomers, at least 50 %, preferably 70 % homology with sequences (i) and (ii) respectively. The invention also concerns their uses for detecting a retrovirus associated with multiple sclerosis and/or rheumatoid arthritis.
Matériel nucléique, à l'état isolé ou purifié, et fragment nucléotidique, comprenant une séquence nucléotidique choisie dans le groupe qui consiste en (i) les séquences SEQ ID NO: 112, SEQ ID NO:114, SEQ ID NO: 117, SEQ ID NO: 120, SEQ ID NO: 124, SEQ ID NO: 130, SEQ ID NO: 141 et SEQ ID NO: 142, (ii) les séquences complémentaires des séquences (i); et (iii) les séquences équivalentes aux séquences (i) ou (ii), en particulier les séquences présentant pour toute suite de 100 monomères contigus, au moins 50 %, et préférentiellement au moins 70 % d'homologie avec respectivement les séquences (i) ou (ii), et utilisations pour détecter un rétrovirus associé à la sclérose en plaques et/ou la polyarthrite rhumatoïde.
Bedin Frederic
Komurian-Pradel Florence
Mallet Francois
Mandrand Bernard
Ott Catherine
Bio Merieux
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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