Retroviral protease inhibitor combinations

Details Retroviral protease inhibitor combinations Retroviral protease inhibitor combinations

A - Human Necessities

61

K

A61K 38/06 (2006.01) A61K 31/16 (2006.01) A61K 31/18 (2006.01) A61K 31/195 (2006.01) A61K 31/34 (2006.01) A61K 31/40 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/505 (2006.01) A61K 31/55 (2006.01) A61K 38/05 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2191948

The present invention is directed to a method for the treatment of mammalian retrovirus infections, such as HIV, using combinations of retroviral protease inhibitors which are effective in preventing the replication of the retroviruses in vitro or in vivo. This invention, in particular, relates to protease inhibitor compounds used in combination therapy with other protease inhibitor compounds. This invention also relates to combination therapy with a combination of protease inhibitors and antiviral agents other than protease inhibitors.

L'invention concerne une méthode de traitement d'infections par rétrovirus chez les mammifères, tels que le VIH, à l'aide d'associations d'inhibiteurs de protéase rétrovirale qui sont efficaces pour prévenir la réplication in vivo ou in vitro des rétrovirus. L'invention porte, plus particulièrement, sur des composés inhibiteurs de protéase utilisés dans une thérapie d'association avec d'autres composés inhibiteurs de protéase, ainsi que sur une thérapie d'association fondée sur une association d'inhibiteurs de protéase et d'agents antiviraux autres que les inhibiteurs de protéase.

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