Retroviral recombination assays and uses thereof

Details Retroviral recombination assays and uses thereof Retroviral recombination assays and uses thereof

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01) C07K 14/15 (2006.01) C12N 15/85 (2006.01) C12N 15/867 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2379207

Methods, systems, and cells are described that can be used to sensitively monitor for retroviral recombination. Using the invention, recombinant proviruses can be detected to provide an evaluation of the risk of creating a replication competent retrovirus (RCR) in vivo. The invention can further be used to improve on existing procedures in the art, including Tat transfer, Gag transfer, and marker rescue and mobilization assays.

L'invention concerne des méthodes, des systèmes et des cellules pouvant être utilisés pour surveiller sensiblement la recombinaison rétrovirale. L'invention permet de détecter des provirus recombinants afin d'évaluer le risque de création d'un rétrovirus de réplication compétent (RCR) in vivo. L'invention peut également être utilisée pour perfectionner les techniques existant déjà dans ce domaine, y compris le transfert de Tat, le transfert de Gag, et les bioanalyses de récupération et de mobilisation du marqueur.

Affiliated with

Also associated with

Rating

Retroviral recombination assays and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Retroviral recombination assays and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Retroviral recombination assays and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1565624