Retroviral vector and its use in the production of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/86 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 7/04 (2006.01) C12N 15/867 (2006.01) C12N 15/89 (2006.01)

Patent

CA 2045480

2045480 9008832 PCTABS00001 Retroviral vectors carrying foreign nucleic acid and having a Feline Leukaemia Virus B env gene product can be introduced into the embryos of sheep and pigs. The foreign nucleic acid is incorporated into the embryo chromosomes, producing transgenic animals. Introduction of a retroviral vector into any embryo is improved by injecting it through the zona pellucida into the perivitelline space.

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