C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/572 (2006.01) A61K 31/395 (2006.01) A61K 38/04 (2006.01) C07D 207/16 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07K 5/02 (2006.01) C07K 5/04 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2043143
ABSTRACT Retrovirally active new anhydrostatin phosphono- pyrrolidines and piperidines of the formula Image (I) in which W - is . hydrogen or a typical amino protecting group, or - is straight-chain or branched alkyl or alkenyl in each case having up to 6 carbon atoms, which are optionally substituted by aryl having 6 to 10 carbon atoms, or - is a group of the formula R3-Co-, R5R4N-Co- or R6-SO2-, A, B and D are identical or different and each - represent a direct bond or - represent a radical of the formula Image , Image or Image , or - represent a group of the formula Image R1 - is cycloalkyl having 3 to 8 carbon atoms, - is straight-chain or branched alkyl or alkenyl having up to 10 carbon atoms, which are optionally substituted by cycloalkyl having 3 to 8 carbon. atoms or aryl having 6 to 10 carbon atoms, which is optionally substituted by halogen, nitro, hydroxyl, amino or straight-chain or branched alkoxy having up to 6 carbon atoms, n - the number 1 or 2, R2- a radical of the formula O=?R11R11', -CO-Rl7 or -CO-NR4R5, in which R4, R5, R11 and R11' have the abovementioned meanings, and R17 - denotes straight-chain or branched alkoxy having up to 8 carbon atoms, which is option- ally substituted by phenyl, and their physiologically acceptable salts.
Habich Dieter
Hansen Jutta
Henning Rolf
Paessens Arnold
Aktiengesellschaft Bayer
Fetherstonhaugh & Co.
Habich Dieter
Hansen Jutta
Henning Rolf
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