Retrovirus inhibition with antisense nucleic acids...

Details Retrovirus inhibition with antisense nucleic acids... Retrovirus inhibition with antisense nucleic acids...

C - Chemistry, Metallurgy

12

N

C12N 15/48 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12N 15/90 (2006.01)

Patent

CA 2107789

2107789 9217211 PCTABS00016 Antisense nucleic acid molecules are provided which hybridize essentially only to the packaging sequence of a retrovirus and thereby inhibit the packaging of the retroviral genomic RNA. The antisense molecules may be DNA, RNA, or analogues thereof. The antisense molecules may be administered as drugs, or the individual to be protected may be genetically manipulated to express an antisense RNA.

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