Retrovirus isolated from humans

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/48 (2006.01) A61K 31/7088 (2006.01) A61K 39/21 (2006.01) A61K 48/00 (2006.01) C07K 14/15 (2006.01) C07K 16/10 (2006.01) C12N 7/00 (2006.01) C12N 15/867 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2426348

The present invention comprises spumavirus isolated from humans. More specifically, the spumavirus of the present invention was isolated from humans who had exposure to nonhuman primates. Importantly, the spumavirus of the present invention or antibodies to the spumavirus can be used to detect the presence of spumavirus or antibodies in body fluids, for pathogenicity studies of related viruses, and as a vector for gene therapies. The spumavirus of the invention can also be used for treatment of conditions in humans due to the presence of rapidly dividing cells and for recombinant live virus vaccination.

La présente invention porte sur un spumavirus isolé chez l'homme. Le spumavirus de cette invention a notamment été isolé chez des être humains ayant été en contact avec des primates. Le spumavirus de l'invention ou les anticorps contre le spumavirus peut être surtout utilisé pour détecter la présence du spumavirus ou des anticorps dans les fluides biologiques en vue de faire des recherches sur la pathogénicité de virus apparentés, et peut être aussi utilisé comme vecteur dans des thérapies géniques. Le spumavirus de l'invention peut être en outre utilisé dans le traitement d'états pathologiques affectant l'homme et imputables à la présence de cellules se divisant rapidement, ainsi que dans la vaccination contre des virus actifs recombinants.

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