C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) C07K 14/15 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2454879
The present invention features an isolated, intact virus associated with human lymphoma, and originally isolated from a mantle cell lymphoma, referred to herein as a mantle histiocyte retrovirus (MHRV). The invention also features compositions and methods for detecting MHRV, as well as methods and compositions for propagating MHRV in vitro, screening for anti-MHRV agents, and generation of attenuated MHRV strains.
L'invention porte sur un virus intact isolé associé au lymphome humain et originellement isolé d'un lymphome de cellule du manteau, dit rétrovirus d'histiocyte du manteau (MHRV). L'invention porte également sur des compositions et procédés de détection du MHRV, et sur des procédés et compositions de propagation du MHRV in vitro et de criblage d'agents anti-MHRV, et sur la production de souches atténuées de MHRV.
Herndier Brian
Mcgrath Michael S.
Fetherstonhaugh & Co.
The Regents Of The University Of California
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