Reversal of female sexual phenotype in poultry

A - Human Necessities – 61 – K

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167/101, 167/208

A61K 31/395 (2006.01) A61K 31/00 (2006.01) A61K 31/44 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2032227

JLT1aY 18024Y TITLE OF THE INVENTION REVERSAL OF FEMALE SEXUAL PHENOTYPE IN POULTRY ABSTRACT OF THE INVENTION Fertilized poultry embryos are treated with steroid biosynthesis inhibitors or antagonists which prevents the conversion of androgens to estrogens. By blocking the production of estrogens the genotypic female is converted into a phenotypic male. The phenotypic conversion of females to males gives the treated birds the advantage of male growth characteristics. A single administration of a steroid biosynthesis inhibitor or antagonist prior to about day 9 of embryonic incubation results in an irreversible change the sexual phenotype.

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