A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/06 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 49/00 (2006.01)
Patent
CA 2222063
A polar liquid-in-perfluorochemical emulsion or microemulsion for use in delivery of therapeutic or diagnostic agents. These compositions are formed by combining a discontinuous aqueous phase, a continuous fluorocarbon phase and a nonfluorinated surfactant. Further, the polar liquid-in-fluorochemical emulsions may be used to form multiple emulsions having an aqueous continuous phase. Such emulsions and microemulsions are suitable for the administration of pharmaceutical agents including genetic material.
Cette invention se rapporte à une émulsion ou microémulsion d'un liquide polaire dans une substance perfluorochmique destinée à servir dans l'administration d'agents thérapeutiques ou diagnostiques. On forme ces compositions en combinant une phase aqueuse discontinue, une phase de fluorocarbone continue et un tensioactif non fluoré. On peut en outre utiliser ces émulsions d'un liquide polaire dans une substance fluorochimique pour former des émulsions multiples ayant une phase continue aqueuse. Ces émulsions et microémulsions sont appropriées pour l'administration d'agents pharmaceutiques, y compris du matériel génétique.
Dellamary Luis A.
Hopper Gina M.
Kabalnov Alexey
Klein David H.
Pelura Timothy J.
Alliance Pharmaceutical Corp.
Sim & Mcburney
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