Rhamm peptide conjugates

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01)

Patent

CA 2406593

The present invention provides protein conjugates having a glucose-aminoglycan- targeting domain conjugated directly or indirectly to a therapeutically useful protein via chemical or peptidyl linkage. The protein conjugates selectively target certain tissues and organs and are useful for treating or preventing various physiological and pathological conditions. Methods of their use and preparation are described.

La présente invention porte sur des conjugués de protéine possédant un domaine ciblant glucose-aminoglycan conjugué directement ou indirectement à une protéine thérapeutiquement utile via une liaison chimique ou peptidyle. Les conjugués de protéine ciblent sélectivement certains tissus et organes et sont utiles dans le traitement ou la prévention de divers états physiologiques et pathologiques. L'invention porte également sur leurs procédés d'utilisation et de préparation.

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