C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/91 (2006.01) A61K 51/04 (2006.01) C07C 251/38 (2006.01) C07D 277/58 (2006.01) C07D 307/73 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07F 13/00 (2006.01) A61K 49/02 (1990.01)
Patent
CA 2081637
Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and a complexing ligand having the general formula Ia, Ib or Ic, (see formula I) wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.
Di Rocco Richard J.
Linder Karen
Nowotnik David P.
Nunn Adrian D.
Pirro John P.
Bracco International B.v.
Di Rocco Richard J.
Linder Karen
Nowotnik David P.
Nunn Adrian D.
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