Rhinosinusitis prevention and therapy with proinflammatory...

A - Human Necessities – 61 – K

Patent

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A61K 9/14 (2006.01) A61M 15/08 (2006.01)

Patent

CA 2657581

The invention describes a method of treating upper airway disease by administering a composition of one or more proinflammatory cytokine inhibitors sufficient to inhibit inflammation in the upper airways. The proinflammatory cytokines that are inhibited include TNF, IL-1 and IL-8. A medication dispensing unit which includes a container and a delivery system is used to administer the composition. The delivery system further encompasses a one-way valve, a microcatheter, or a liquid-pressure type sprayer.

L'invention concerne un procédé de traitement des maladies des voies respiratoires supérieures en administrant une composition d'un ou plusieurs inhibiteurs de cytokine proinflammatoires suffisants pour inhiber l'inflammation dans les voies respiratoires supérieures. Les cytokines proinflammatoires qui sont inhibées comprennent du TNF, IL-1 et IL-8. Une unité de distribution de médicament qui comprend un conteneur et un système de distribution est utilisée pour administrer la composition. Le système de distribution comprend en outre une soupape monovalente, un micro-cathéter, ou un vaporisateur de type à pression liquide.

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