Rhizoxin derivatives, their preparation and pharmaceutical use

Details Rhizoxin derivatives, their preparation and pharmaceutical use Rhizoxin derivatives, their preparation and pharmaceutical use

C - Chemistry, Metallurgy

07

D

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C07D 493/00 (2006.01) C07D 493/04 (2006.01) C07D 493/14 (2006.01) C07D 493/18 (2006.01) C07D 493/22 (2006.01)

Patent

CA 1271763

ABSTRACT OF THE DISCLOSURE Acylated derivatives of rhizoxin and of the formula wherein: Image (I) R represents an alkyl group having at least 2 carbon atoms; and A represents an extra carbon-carbon bond or an oxygen atom and pharmaceutically acceptable salts and ring-closed lactones thereof have excellent anti-tumour activity.

503062

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