C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
167/184, 260/208
C07H 15/252 (2006.01) A61K 31/65 (2006.01)
Patent
CA 2015398
-1- Abstract of the disclosure Rhodomycin derivatives with cytostatic activity The invention relates to new anthracycline derivatives with cytostatic activity and the formula I Image and the physiologically acceptable salts thereof, where R1 is hydrogen or a hydroxyl group and R2 is NRa- ( CH2 ) n- NRaRb, with n = 0-12, where Ra and Rb are hydrogen, C1-C4- alkyl or benzyl, or R2 is NRa-CHR3-CH2-R4, where Ra has the said meaning and R3 is hydrogen or a carboxyl group and R4 is the residue of an L-amino acid or of a biogenic amine, a process for the preparation thereof and the use thereof in a pharmaceutical.
Czech Jorg
Hermentin Peter
Kraemer Hans P.
Raab Ernst
Behringwerke Aktiengesellschaft
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Czech Jorg
Hermentin Peter
Kraemer Hans P.
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