Rhodomycin-group of antibiotics and process for preparing same

C - Chemistry – Metallurgy – 12 – P

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195/103, 260/208

C12P 19/56 (2006.01) C07H 15/252 (2006.01) C12P 15/00 (2006.01)

Patent

CA 1156578

ABSTRACT OF THE DISCLOSURE: The invention relates to a process for preparing anthracycline glycoside derivatives of rhodomycin- group, .epsilon.-rhodomycin RDC, .epsilon.-isorhodomycin RDC, .beta.-rhodomycin RDC or .gamma.-rhodomycin RDC by microbiological conversion, with Streptomyces galilaeus KM 303. The invention also relates to these anthracycline glycoside derivatives of rhodomycin group having potent anticancer activities and lower toxicities.

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