Rhodomycins with a modified carbohydrate unit

Details Rhodomycins with a modified carbohydrate unit Rhodomycins with a modified carbohydrate unit

C - Chemistry, Metallurgy

07

H

260/208.1

C07H 15/252 (2006.01)

Patent

CA 2005932

-1- BEHRINGWERKE AKTIENGESELLSCHAFT 88/B 044 - Ma 732 Dr. Ha/Sd ABSTRACT OF THE DISCLOSURE Rhodomycins with a modified carbohydrate unit 7-0-Glycosyl-rhodomycins which correspond to the general formula I below Image Formula I in which the radicals have the following meaning: R1 is a hydrogen atom or a hydroxyl group, R2 is a hydrogen atom or a C1-C4 alkyl group, R3 is a hydroxyl group, an O-acyl protective group or the methyloxycarbonyl group, R4 is a hydrogen atom, an O-acyl protective group, an azido group, amino or trifluoroacetylamino group, a di-C1-C4-alkylamino group or cyanomethylamino group and R5 is an azido group, amino or trifluoroacetylamino group, a di-C1-C4-alkylamino group or cyanomethyl- amino group, where acyl protective group denotes an acetyl, mono-, di- or trihalogenoacetyl group with fluorine or chlorine as halogen or the p-nitrobenzoyl group, and a process for the preparation thereof and the use thereof as phar- maceuticals, are described.

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