Ribozyme therapy for restenosis

Details Ribozyme therapy for restenosis Ribozyme therapy for restenosis

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C12N 9/22 (2006.01) C12N 15/86 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2184989

As an effective therapy for restenosis, this invention provides ribozymes and ribozyme delivery systems useful to inhibit abnormal smooth muscle cell proliferation in vascular tissue. Methods of producing ribozymes and gene therapy utilizing these ribozymes also are provided.

Pour traiter efficacement la resténose cette invention utilise des ribozymes et des systèmes d'apport de ribozymes utiles pour inhiber la prolifération anormale de cellules de muscles lisses dans les tissus vasculaires. Des procédés de production de ribozymes et de thérapie génique dans lesquels on utilise ces ribozymes sont également décrits.

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