Ribozyme treatment of diseases or conditions related to...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 31/70 (2006.01) C07H 21/02 (2006.01) C12N 5/10 (2006.01) C12N 9/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2199727

Enzymatic RNA molecules which cleave apo(a) mRNA. Use of these catalytic RNA molecules for the treatment of conditions related to lipoprotein A levels, such as atherosclerosis, myocardial infarction, strokes; testenosis and heart diseases.

Molécules enzymatiques d'ARN assurant le clivage de l'ARNm apo(a). Utilisation de ces molécules d'ARN catalytiques pour traiter des états liés au niveau des lipoprotéines A, tels que l'athérosclérose, l'infarctus du myocarde, les ictus, la resténose et les troubles cardiaques.

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