Ribozymes capable of inhibiting the expression of the ccr5...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/11 (2006.01) A61K 31/70 (2006.01) C07K 14/715 (2006.01) C12N 5/10 (2006.01) C12N 9/00 (2006.01) C12N 15/86 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2323109

This invention provides ribozymes and combinations thereof, to cleave RNA sequences. The invention also provides a method of treating HIV-1 by down- regulating the CCR5 receptor.

La présente invention concerne des ribozymes et des combinaisons associées, destinés à couper des séquences d'ARN. Cette invention concerne aussi un procédé de traitement contre le HIV-1 par régulation négative du récepteur CCR5.

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