C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/235.82
C07D 498/22 (2006.01)
Patent
CA 1089453
ABSTRACT OF THE DISCLOSURE: The present invention relates to novel Rifamycin compounds of formula I; Image (I) wherein R is a radical selected from the group consisting of hydrogen, linear C4- C8 alkyl, branched C3-C8 alkyl, C3-C4 alkenyl, C3-C6 cycloalkyl, C7-C8cycloalkyl-alkyl, C3-C7 alkoxyalkyl, C5-C6 alkyl-furyl, C5-C6 alkyl-tetrahydrofuryl, C5-C6 alkanoyl, C2-C6monohaloalkanoyl, and Y is - H or COCH3, and their process of preparation. These compounds have high antibiotic activity, particularly on Mycobacterium Tuberculosis.
304380
Marsili Leonardo
Pasqualucci Carmine
Rossetti Vittorio
Archifar Laboratori Chimico Farmacologici S.p.a.
Farmitalia Carlo Erba S.r.l
Robic Robic & Associes/associates
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