Rifamycin compounds

C - Chemistry – Metallurgy – 07 – D

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260/235.82

C07D 498/22 (2006.01)

Patent

CA 1089453

ABSTRACT OF THE DISCLOSURE: The present invention relates to novel Rifamycin compounds of formula I; Image (I) wherein R is a radical selected from the group consisting of hydrogen, linear C4- C8 alkyl, branched C3-C8 alkyl, C3-C4 alkenyl, C3-C6 cycloalkyl, C7-C8cycloalkyl-alkyl, C3-C7 alkoxyalkyl, C5-C6 alkyl-furyl, C5-C6 alkyl-tetrahydrofuryl, C5-C6 alkanoyl, C2-C6monohaloalkanoyl, and Y is - H or COCH3, and their process of preparation. These compounds have high antibiotic activity, particularly on Mycobacterium Tuberculosis.

304380

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