Rig-i mutations and uses thereof in diagnostic and...

Details Rig-i mutations and uses thereof in diagnostic and... Rig-i mutations and uses thereof in diagnostic and...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 45/00 (2006.01) A61P 31/12 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2660622

The invention relates to the identification of RIG-I dysfunctions as being responsible for a subject susceptibility to develop a viral infection. Described are nucleic acid molecules, mutated RIG-I proteins, probes, kits, diagnostic methods and therapeutic applications related to the identification of mutations in the RIG-I gene.

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