Ring-contracted macrolides

Details Ring-contracted macrolides Ring-contracted macrolides

C - Chemistry, Metallurgy

07

H

167/185, 260/230

C07H 17/08 (2006.01) A61K 31/70 (2006.01)

Patent

CA 1321581

ABSTRACT OF THE INVENTION Novel 12-membered lactone and ll-membered lactone derivatives of erythromycin and the salts and ester derivatives of these compounds. The new erythromycin lactones have antimicrobial activity against certain Gram-positive pathogens such as Streptococcus Pyogenes and Gram-negative cocci such as Haemophilus influenzae. In addition, they are useful as intermediates to other macrolide derivatives.

567523

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