Ring-contracted macrolides

Details Ring-contracted macrolides Ring-contracted macrolides

C - Chemistry, Metallurgy

07

H

167/185, 260/230

C07H 17/08 (2006.01) A61K 31/71 (1990.01)

Patent

CA 2009370

X-7133A Abstract of the Invention Novel 12-membered lactone and 11-membered lactone derivatives of erythromycin, having antimicrobial activity against certain Gram-positive pathogens such as Streptococcus pyogenes and Gram-negative cocci such as Haemophilus influenzae, and useful as intermediates to other macrolide derivatives, are disclosed.

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