Risedronate sodium having a very low content of iron

Details Risedronate sodium having a very low content of iron Risedronate sodium having a very low content of iron

C - Chemistry, Metallurgy

07

F

C07F 9/59 (2006.01)

Patent

CA 2513543

The present invention relates to a method of making risedronate sodium substantially free of iron including the steps of refluxing, especially with mechanical agitation, a combination of risedronic acid, a sodium base, especially sodium hydroxide, and an iron-reducing amount of EDTA in a liquid that is water, a lower alkanol, or, especially, a mixture of a lower alkanol and water; and isolating risedronate sodium substantially free of iron from the combination.

L'invention concerne un procédé de préparation de risédronate sodium, essentiellement exempt de fer, selon lequel il est prévu les étapes suivantes : faire bouillir au reflux, notamment par agitation mécanique, une combinaison d'acide risédronique, une base de sodium, notamment de l'hydroxyde de sodium et un volume réducteur de fer d'EDTA dans un liquide qui est de l'eau, un alcanol inférieur ou, en particulier, un mélange d'alcanol inférieur et d'eau ; isoler le risédronate sodium sensiblement exempt de fer de la combinaison.

Affiliated with

Also associated with

Rating

Risedronate sodium having a very low content of iron does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Risedronate sodium having a very low content of iron, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Risedronate sodium having a very low content of iron will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1345229