Rna interference mediated inhibition of gene expression...

C - Chemistry – Metallurgy – 07 – H

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07H 21/04 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2455447

The present invention concerns methods and reagents useful in modulating gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the invention relates to small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double- stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules capable of mediating RNA interference (RNAi) against target nucleic acid sequences. The small nucleic acid molecules are useful in the treatment of any disease or condition that responds to modulation of gene expression or activity in a cell, tissue, or organism.

L'invention concerne des méthodes et des réactifs utilisés pour moduler une expression génique dans une variété d'applications, notamment dans des applications thérapeutiques, diagnostiques, de validation de cible et de découverte génomique. L'invention concerne, plus spécifiquement, de petites molécules d'acide nucléique, tel qu'un acide nucléique d'interférence court (INA), un ANR d'interférence court (siRNA), un ARN double brins (dsRNA), un micro-ARN (miRNA) et des molécules d'ARN court en épingle à cheveux (shRNA) capables d'induire une médiation d'interférence ARN (RNAi) par rapport à des séquences cibles d'acide nucléique. On utilise ces petites molécules d'acide nucléiques pour traiter une maladie ou un état quelconque répondant à la modulation de l'expression d'un gène ou d'une activité dans une cellule, un tissu, ou un organisme.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Rna interference mediated inhibition of gene expression... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Rna interference mediated inhibition of gene expression..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rna interference mediated inhibition of gene expression... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1864970

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.