C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/02 (2006.01) A61K 31/713 (2006.01) A61P 29/00 (2006.01) A61P 31/14 (2006.01) A61P 35/00 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2523658
The present invention provides compositions and methods that are useful for the treatment of severe acute respiratory syndrome (SARS). More specifically, nucleic acid agents such as siRNA molecules and their analogues that target respiratory infections including SARS coronavirus and their methods of use are described, for clinical treatments of SARS, respiratory viral infections, for prevention and treatment of respiratory infections as needed for bio-defense, for treatment of respiratory diseases, and for discovery of therapeutic targets for respiratory diseases and infections.
L'invention concerne des compositions et des méthodes utilisées pour traiter le syndrome respiratoire aigu (SRAS). L'invention concerne, de manière plus spécifique, des agents d'acides nucléiques tels que des molécules d'ARNsi et leurs analogues ciblant des infections respiratoires induites notamment par le coronavirus SRAS ainsi que leurs méthodes d'utilisation. L'invention permet également de traiter cliniquement le SRAS, les infections respiratoires virales, de prévenir et de traiter les infections respiratoires si nécessaire pour induire une bio-défense, de traiter des maladies respiratoires et de découvrir des thérapeutiques pour maladies et infections respiratoires.
Liu Yijia
Lu Patrick Y.
Tang Quinn T.
Woodle Martin C.
Xie Frank Y.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Intradigm Corporation
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