Rnai inhibition of alpha-enac expression

Details Rnai inhibition of alpha-enac expression Rnai inhibition of alpha-enac expression

C - Chemistry, Metallurgy

12

N

C12N 15/113 (2010.01) A61K 31/713 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2690674

The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides.

L'invention concerne des compositions et des méthodes permettant de moduler l'expression du canal alpha-ENaC et, plus particulièrement, de réguler à la baisse l'expression du canal alpha-ENaC à l'aide d'oligonucléotides modifiés par voie chimique.

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