Rnai-mediated inhibition of gremlin for treatment of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 31/7105 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2659464

RNA interference is provided for inhibition of gremlin in intraocular pressure-related conditions, including ocular hypertension and glaucoma such as normal tension glaucoma and open angle glaucoma.

Selon la présente invention, l'interférence ARN est utilisée pour l'inhibition de la gremline dans le cas d'affections liées à la pression intraoculaire, y compris l'hypertension oculaire et le glaucome, tel que le glaucome à tension normale et le glaucome à angle ouvert.

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