Rnai modulation of apob and uses thereof

Details Rnai modulation of apob and uses thereof Rnai modulation of apob and uses thereof

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 31/70 (2006.01) C12N 5/00 (2006.01)

Patent

CA 2580707

The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides.

L'invention concerne des compositions et des méthodes destinées à moduler l'expression de l'apolipoprotéine B, et plus particulièrement la régulation négative de l'apolipoprotéine B au moyen d'oligonucléotides modifiés chimiquement.

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