C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) G06F 17/50 (2006.01) G06N 3/10 (2006.01)
Patent
CA 2545675
Methods for making an algorithm for the prediction of the RNAi potency of a RNAi reagent are provided. Also provided are methods for predicting the RNAi potency of a RNAi reagent and methods for inhibiting the expression of a given target gene using such an algorithm.
L'invention concerne des procédés permettant de mettre au point un algorithme pour prédire l'efficacité de l'ARNi d'un réactif ARNi. L'invention concerne également des procédés permettant de prédire l'efficacité d'un réactif ARNi, ainsi que des procédés permettant d'inhiber l'expression d'un gène cible donné, à l'aide d'un tel algorithme.
Hall Jonathan
Huesken Dieter
Lange Joerg Bernd
Natt Francois Jean-Charles
Reinhardt Mischa Werner Henri Marie
Fetherstonhaugh & Co.
Novartis Ag
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