Rocaglaol derivatives as cardioprotectant agents and as...

Details Rocaglaol derivatives as cardioprotectant agents and as... Rocaglaol derivatives as cardioprotectant agents and as...

C - Chemistry, Metallurgy

07

D

C07D 307/93 (2006.01) A61K 31/343 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2744309

The present invention discloses new rocaglaol derivatives and the use of rocaglaol derivatives to prevent or to limit the cardiotoxicity of an antineoplastic agent, in particular to prevent or to limit the apoptosis of cardiomyocytes induced by such agent.

La présente invention porte sur de nouveaux dérivés du rocaglaol et sur l'utilisation de dérivés du rocaglaol pour empêcher ou limiter la cardiotoxicité d'un agent antinéoplasique, en particulier pour empêcher ou limiter l'apoptose de cardiomyocytes induite par un tel agent.

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