Rod shaped apatite crystals with a specific length-to-width...

C - Chemistry – Metallurgy – 01 – B

Patent

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Details

C01B 25/32 (2006.01) A23G 4/00 (2006.01) A61K 6/033 (2006.01) A61K 8/21 (2006.01) A61K 8/24 (2006.01) A61L 27/12 (2006.01) A61L 27/32 (2006.01) A61L 27/42 (2006.01) A61Q 11/00 (2006.01) C01B 25/455 (2006.01)

Patent

CA 2451554

The invention relates to rod-shaped apatite crystals of formula Ca5(PO4)3(OH)x F y, comprising the following characteristics: a) the length-to-width-ratio of the crystal is at least >= 5 and b) x + y represent 1, in the case where x or y 0, the total amount of the crystals exist as single hydroxylapatite crystals and fluorapatite crystals and/or as a mixture of mixed crystals, whereby in relation to the total amount of the crystals, (1 - x). 100 % of the hydroxidions are replaced by fluoridions in the case where y = 0. The invention also relates to dispersions which contain said rod-shaped apatite crystals, in addition to a method for producing said dispersions or apatite crystals.

L'invention concerne des cristaux d'apatite en forme de baguette de formule Ca5(PO4)3(OH)xFy, présentant plusieurs particularités : a) le rapport longueur/largeur des cristaux est au moins supérieur ou égal à 5 ; et b) x+ y = 1, la quantité totale des cristaux existant sous la forme d'un mélange de cristaux d'hydroxylapatite et de cristaux de fluoroapatite et/ou de cristaux mixtes, dans le cas où x ou y diffèrent de 0, de façon que, par rapport à la quantité totale des cristaux, (1 x) <100 % des hydroxidiones présentes, dans le cas où y équivaut à 0, sont remplacées par des fluoridiones. L'invention concerne en outre des dispersions, contenant lesdits cristaux d'apatite en forme de baguette ainsi qu'un procédé de production desdites dispersions ou bien des cristaux d'apatite.

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