Roles for dual endothelin-1/angiotensin ii receptor (dear)...

Details Roles for dual endothelin-1/angiotensin ii receptor (dear)... Roles for dual endothelin-1/angiotensin ii receptor (dear)...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 38/18 (2006.01) A61K 38/22 (2006.01) A61K 39/395 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01) C12N 15/16 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2588066

The present application is directed to the identification of mutations and/or polymorphisms in the Dual Endothelin-l/Angiotensin II Receptor (Dear) that indicate susceptibility to, or show current affliction with, hypertension. Additionally, the present invention discloses methods for the modulation of angiogenesis via the regulation of Dear.

La présente invention concerne l'identification de mutations et/ou de polymorphismes affectant le récepteur Dear (Dual Endothelin-l/Angiotensin II Receptor), ces mutations et polymorphismes témoignant d'une hypertension possible ou installée. L'invention concerne également une régulation du récepteur Dear visant à moduler l'angiogenèse.

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