C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/46 (2006.01) A61K 39/15 (2006.01) C07K 14/14 (2006.01) C12N 7/00 (2006.01) C12N 7/01 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2065847
The present invention provides novel rotavirus. reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. The reassortant contains the gene encoding the v.p.4 neutralization antigen of a selected hu- man rotavirus and/or the gene encoding the v.p.7 neutralization antigen of a selected human rotavirus, with remaining genes be- ing provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.
Clark H. Fred
Offit Paul
Plotkin Stanley A.
Gowling Lafleur Henderson Llp
The Children's Hospital Of Philadelphia
The Wistar Institute Of Anatomy And Biology
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