A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/15 (2006.01) A61K 9/00 (2006.01) C07K 14/14 (2006.01) C12N 7/00 (2006.01) C12N 7/08 (2006.01)
Patent
CA 2379196
The invention provides an attenuated rotavirus population comprising a single variant or substantially a single variant which is defined by a nucleotide sequence encoding at least one of the major viral proteins designated as VP4 and VP7. The invention particularly provides a rotavirus population designated as P43. The invention further provides a novel formulation for a rotavirus vaccine which is in the form of a quick dissolving tablet for immediate dissolution when placed on the tongue.
L'invention concerne une population virale de rotavirus atténué comprenant une seule variante ou sensiblement une seule variante qui est définie par une séquence nucléotidique codant pour au moins une des protéines virales majeures suivantes : VP4 et VP7. D'une manière spécifique, l'invention concerne une population de rotavirus nommée P43. L'invention concerne également une nouvelle formulation d'un anti-rotavirus qui se présente sous la forme d'un comprimé destiné à se dissoudre rapidement sur la langue.
Colau Brigitte Desiree Alberte
Denamur Francoise
Knott Isabelle
Poliszczak Annick
Thiry Georges
Borden Ladner Gervais Llp
Smithkline Beecham Biologicals S.a.
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