Rotogranulations and taste masking coatings for preparation...

Details Rotogranulations and taste masking coatings for preparation... Rotogranulations and taste masking coatings for preparation...

A - Human Necessities

61

K

A61K 9/62 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 31/34 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2052679

Chewable medicament tablets are made from coated rotogranules of a medicament wherein the rotogranules are formed from a granulation mixture of medicament, e.g. famotidine binder, e.g. polyvinylpyrrolidone, and carrier, e.g. lactose and the rotogranules are coated with cellulose acetate, cellulose acetate butyrate or a combination thereof and polyvinyl pyrrolidone and a process for making such tablets and a method of providing taste masking of medicaments utilizing such coated rotogranules.

Comprimés médicamenteux à croquer faits de rotogranules enrobés d'un médicament; les rotogranules sont formés à partir d'un mélange de granules du médicament, p. ex. liant de famotidine, p. ex. polyvinylpyrrolidone, et d'un transporteur, p. ex. lactose, et les rotogranules sont enrobés avec de l'acétate de cellulose, de l'acétobutyrate de cellulose ou une combinaison de ces derniers et de la polyvinylpyrrolidone; procédé pour fabriquer de tels comprimés et méthode pour fournir un moyen de masquer le goût des médicaments à l'aide de tels rotogranules enrobés.

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