Rotomelt granulation

Details Rotomelt granulation Rotomelt granulation

A - Human Necessities

61

K

A61K 9/16 (2006.01) B01J 2/14 (2006.01) B01J 2/16 (2006.01)

Patent

CA 2099076

A process for producing granules by rotomelt granulation comprising mixing at least one powdered pharmaceutically active material and a powdered excipient material within a zone wherein both powdered materials are maintained in a fluidized state by a rising stream of gas in an apparatus having a rapidly rotating horizontal-disk located within a vertical vessel wherein said gas is at a temperature sufficient to cause at least one powdered material to at least partially melt thereby causing said powdered materials to aggregate and form granules.

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