Rotor and method for automatically processing liquids for...

G - Physics – 01 – N

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G01N 21/07 (2006.01) B01L 3/00 (2006.01)

Patent

CA 2053894

2053894 9015321 PCTABS00002 A rotor assembly (50) for performing a relatively large number of processing steps upon a sample, such as a whole blood sample, and a diluent, such as water, includes a rotor body (52) for rotation about an axis (R) and including a network of chambers within which various processing steps are performed upon the sample and diluent; and passageways through which the sample and diluent; are transferred. A transfer mechanism (60) is movable through the rotor body by the influence of a magnetic field generated adjacent the transfer mechanism and movable along the rotor body, and the assembly utilizes centrifugal force, a transfer of momentum and capillary action to perform any of a number of processing steps such as separation, aliquoting, transference, washing, reagent addition and mixing of the sample and diluent within the rotor body. The rotor body is particularly suitable for automatic immunoassay analyses.

Elément-rotor (50) capable d'effectuer un nombre relativement élevé d'opérations sur un échantillon, par exemple échantillon de sang total, et sur un diluant, par exemple de l'eau. Il comprend un corps de rotor (52) pivotant autour d'un axe (R) et doté d'une série de chambres dans lesquelles sont effectuées diverses opérations de traitement sur l'échantillon et sur le diluant, ainsi que des passages par lesquels transitent lesdits échantillons et diluants. Un mécanisme de transfert (60) peut se déplacer à travers le corps de rotor sous l'influence d'un champ magnétique créé contigu à ce mécanisme et que l'on peut déplacer le long du corps de rotor. Cet élément utilise la force centrifuge, un transfert d'énergie cinétique et d'action capillaire, pour accomplir une ou plusieurs des opérations de traitement, telles que séparation, échantillonage, transfert, lavage, addition de réactifs et mélange de l'échantillon et du diluant, le tout dans le corps de rotor. Celui-ci est particulièrement bien adapté aux analyses automatiques d'immuno-dosage.

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