C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/00 (2006.01) A61K 47/48 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2068325
2068325 9107182 PCTABS00005 The present invention relates to a method of inhibiting protein synthesis comprising contacting 28S rRNA of a protein synthesizing system with a protein synthesis inhibitory amount of an oligonucleotide that hybridizes to the .alpha.-sarcin recognition domain loop of said 28S rRNA under conditions such that hybridization occurs. The invention also relates to oligonucleotides suitable for use in such a method.
Ackerman Eric J.
Saxena Shailendra K.
Gowling Lafleur Henderson Llp
U.s. Department Of Commerce United States Of America Represented By The Secretary
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