Rsv f-protein and its use

Details Rsv f-protein and its use Rsv f-protein and its use

C - Chemistry, Metallurgy

12

N

C12N 15/45 (2006.01) A61K 39/155 (2006.01) C07K 14/135 (2006.01) C12N 15/85 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2673373

The present invention relates to a nucleic acid molecule, which codes for the F-protein of the respiratory syncytial virus (RSV) or a fragment thereof, for the expression in a human cell environment of codon optimized variants of said nucleic acid molecule, vectors and compositions comprising said nucleic acid molecules and the use thereof as vaccines and polypeptides coded by the nucleic acid molecules and method for the production thereof.

L'invention concerne une molécule d'acide nucléique qui est codée pour la protéine F du virus respiratoire syncytial (RSV) ou un fragment de celle-ci, pour l'expression dans un environnement cellulaire humain de variantes à codon optimisé de cette molécule d'acide nucléique. L'invention concerne également des vecteurs et des compositions qui contiennent ces molécules d'acide nucléique, et leur utilisation comme vaccins, ainsi que les polypeptides codés par les molécules d'acide nucléique, et des procédés pour leur fabrication.

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