Ruthenium compounds and compositions

A - Human Necessities – 61 – K

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A61K 47/48 (2006.01) A61K 33/24 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2714547

Ruthenium containing compounds and compositions which inhibit the cellular mitochondrial electron transfer mechanism by providing electrochemically-generated oxygen to an oxygen- deprived environment. Also provided are pharmaceutical compositions containing the same and methods for treating cancer using the pharmaceutical compositions.

L'invention porte sur des composés et des compositions contenant du ruthénium. Lesdits composés et compositions inhibent le mécanisme de transfert d'électrons mitochondrial cellulaire en fournissant de l'oxygène généré électrochimiquement à un environnement privé d'oxygène. L'invention porte également sur des compositions pharmaceutiques contenant ces composés et compositions ainsi que sur des procédés de traiter du cancer par administration desdites compositions pharmaceutiques.

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